A model international partnership for community-based research on vaccine-preventable diseases: the Kamphaeng Phet-AFRIMS Virology Research Unit (KAVRU).

Robert V Gibbons,Ananda Nisalak,In-Kyu Yoon,Darunee Tannitisupawong,Kamchai Rungsimunpaiboon,David W Vaughn,Timothy P Endy,Bruce L Innis,Donald S Burke,Mammen P Mammen,Robert McNair Scott,Stephen J Thomas,Charles H Hoke

Vaccine（2013）

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摘要

•A 30 year international collaboration has provided many benefits.•Efficacy trials of Japanese encephalitis and Hepatitis A vaccines led to regulatory approvals.•Reduction in disease rates occurred in populations in which the vaccines were widely used.•Diagnostic tests were refined, dengue pathogenesis elucidated, and influenza risks identified.•Studies provided model for HIV and HEV vaccine trials done elsewhere.

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关键词

Vaccine efficacy trials,Site selection,Japanese encephalitis vaccine,Hepatitis A vaccine,Dengue vaccine,Influenza,Collaboration,Team building,Public Health

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