Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications.

Hui Wei,Jingjie Mo,Li Tao,Reb J Russell,Adrienne A Tymiak,Guodong Chen,Roxana E Iacob,John R Engen

Drug Discovery Today（2014）

引用 172|浏览6

暂无评分

摘要

•Hydrogen/deuterium exchange mass spectrometry (HDX-MS) technology for assessment of higher order structure of protein therapeutics.•Methodology: global HDX-MS and peptide HDX-MS.•Applications: epitope mapping and comparability study.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要