Effects of mPGES-1 deletion on eicosanoid and fatty acid profiles in mice.

Prostaglandins & Other Lipid Mediators(2013)

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摘要
•We studied effects of mPGES-1 deletion on eicosanoids and fatty acids in mice.•mPGES-1 deletion increased PGD2 metabolites and 13-HODE in peritoneal macrophages.•mPGES-1 depletion altered the total lipid fatty acid composition in mouse spleen.
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关键词
mPGES-1,Prostaglandins E2,Eicosanoids,Fatty acids,Knock-out mice,Inflammation
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