Deciphering the role of stroma in pancreatic cancer

    Current opinion in gastroenterology, Volume 29, Issue 5, 2013, Pages 537-543.

    Cited by: 16|Bibtex|Views1|Links
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    Keywords:
    mesenchymal stromal cellsstromal cells

    Abstract:

    This review intends to describe recent studies on pancreatic tumor-associated stroma and potential opportunities and limitations to its targeting.One of the defining features of pancreatic cancer is extensive desmoplasia, or an inflammatory, fibrotic reaction. Carcinoma cells live in this complex microenvironment which is comprised of ext...More

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