Screening assay for blood vessel maturation inhibitors.

Chenglai Fu,Anita van der Zwan,Stephanie Gerber,Susan Van Den Berg,Elisa No,Wayne C H Wang,Nader Sheibani,Michael A Carducci,Sushant Kachhap,Hans J Hammers

Biochemical and Biophysical Research Communications（2013）

引用 8|浏览14

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摘要

•We model the complex process of blood vessel maturation in vitro.•Process can be observed in real-time.•Format allows for rapid and easy imaging/data acquisition.•System validated by drugs targeting and endothelial cells and pericytes.•Semi-high-throughput allows for drug screening.

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关键词

Angiogenesis model,Pericyte,Imatinib,Sunitinib,Endoglin,Drug screening,Blood vessel maturation

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