Translatome analysis of CHO cells to identify key growth genes.

Franck C Courtes,Joyce Lin,Hsueh Lee Lim,Sze Wai Ng,Niki S C Wong,Geoffrey Koh,Leah Vardy,Miranda G S Yap,Bernard Loo,Dong-Yup Lee

Journal of Biotechnology（2013）

引用 27|浏览4

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摘要

•First use of the translatomic platform in CHO cell culture.•New strategy to identify and prioritize cellular growth biomarkers.•Large decoupling between transcript level and translation efficiency.•Translatome data toward bridging the gap between transcriptome and proteome.

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关键词

Translatome,CHO cells,Polysome profiling,Cellular growth

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