Paramyxovirus infections in ex vivo lung slice cultures of different host species.

D Tien Nguyen,Rory D de Vries,Martin Ludlow,Bernadette G van den Hoogen,Ken Lemon,Geert van Amerongen,Albert D M E Osterhaus,Rik L de Swart,W Paul Duprex

Journal of Virological Methods（2018）

引用 26|浏览11

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摘要

•Agarose-inflated lung slice cultures as a model to study respiratory virus infections.•Agarose-inflated lung slices remain viable at 37°C up to 7 days.•Recombinant viruses expressing EGFP allow real-time monitoring of infection.

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关键词

Lung slices,Respiratory virus,Paramyxovirus,Ex vivo model,Infection,Pathogenesis

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