Endocrine disrupting effects in rats perinatally exposed to a dietary relevant mixture of phytoestrogens.

•High doses of a dietary relevant mixture of phytoestrogens induced endocrine disruption in rats.•Mammary gland histology was altered in adult males after perinatal exposure.•Anti-androgenic effects on anogenital distance were present in newborn males.•An excessive human intake of phytoestrogens from dietary supplements or special dietary habits may contribute to endocrine disruption following exposure during fetal life.