Gastrointestinal pain: unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation.

PAIN®（2013）

引用 63|浏览15

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摘要

Uroguanylin activation of the guanylate cyclase-C/cyclic guanosine monophosphate pathway elicits analgesic effects in animal models of colonic hypersensitivity, unraveling a novel pathway to treat abdominal pain.

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关键词

Cyclic guanosine monophosphate,Gastrointestinal pain,Guanylate cyclase-C,Linaclotide,Uroguanylin

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