T-type Ca2 + channels regulate the exit of cardiac myocytes from the cell cycle after birth

Fang Wang,Hui Gao,Hajime Kubo,Xiaoxuan Fan,Hongyu Zhang,Remus Berretta,Xiongwen Chen,Thomas Sharp,Timothy Starosta,Catherine Makarewich,Ying Li,Jeffrey D. Molkentin,Steven R. Houser

Journal of Molecular and Cellular Cardiology（2013）

引用 16|浏览8

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摘要

T-type Ca2+ channels (TTCCs) are expressed in the fetal heart and then disappear from ventricular myocytes after birth. The hypothesis examined in this study was the α1G TTCCs' influence in myocyte maturation and their rapid withdrawal from the cell cycle after birth.

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关键词

T-type Ca2+ channels,Cardiac myocytes,Cell cycle

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