Novel molecular type of Clostridium difficile in neonatal pigs, Western Australia.

Michele M Squire,Glen P Carter,Kate E Mackin,Anjana Chakravorty,Torbjörn Norén,Briony Elliott,Dena Lyras,Thomas V Riley

EMERGING INFECTIOUS DISEASES（2013）

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摘要

Clostridium difficile causes neonatal enteritis in piglets; strains of PCR ribotype 078 are most commonly identified. We investigated C. difficile prevalence in piglets in Australia and isolated a novel strain with a unique pathogenicity locus. In a mouse infection model, this strain produced more weight loss than did a ribotype 078 strain.

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australia,c. difficile,cdiff,clostridium difficile,dna,pcr,animals,bacteria,diarrhea,domestic,enteritis,piglets,pigs,prevalence,ribotyping,sequence analysis,veterinary,zoonoses,bacterial toxins,survival analysis,polymerase chain reaction

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