A highly reproducible model of cerebral ischemia/reperfusion with extended survival in CB-17 mice.

Yukiko Kasahara,Masafumi Ihara,Takayuki Nakagomi,Yoshihiro Momota,David M Stern,Tomohiro Matsuyama,Akihiko Taguchi

Neuroscience Research（2013）

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摘要

•A highly reproducible cerebral ischemia/reperfusion model with long time survival.•The most benefit is the reproducibility between animals and laboratories.•Our preclinical model can provide various pathological conditions.•It represents a major step forward for testing future therapeutic methods.

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关键词

Stroke model,Transient cerebral ischemia,Ischemia/reperfusion injury,Reproducibility

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