Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice.

Camille Lévy,Laetitia Aerts,Marie-Ève Hamelin,Christelle Granier,Judit Szécsi,Dimitri Lavillette,Guy Boivin,François-Loïc Cosset

Vaccine（2013）

引用 36|浏览21

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摘要

•We designed a new hMPV vaccine based on retroviral virus-like particles.•hMPV-VLP induces cross-neutralizing antibodies.•hMPV-VLPs protects mice from infections with both lineages of hMPV.

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关键词

Metapneumovirus,Vaccine,Virus-like particle,Neutralization,Antibody

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