Sex and lineage interact to predict behavioral effects of chronic adolescent stress in rats.

Behavioural Brain Research(2013)

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摘要
•We examined the effects of chronic adolescent stress in selectively bred rats.•Chronic adolescent stress reduced weight gain in all rats in both lineages and sexes.•Lineage interacted with chronic adolescent stress to dictate activity level.•Stress-induced anhedonia was dependent on lineage.•Sex differences in behavior were attenuated by lineage
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关键词
Forced swim,Stress,Adolescent,Sex,Depressive-like,Selective breeding,Sucrose preference,Stress susceptible,Stress resistant,Open field
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