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Design and Synthesis of 2-N-substituted Indazolone Derivatives As Non-Carboxylic Acid Glycogen Synthase Activators

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS(2013)

引用 34|浏览17
关键词
Glycogen synthase,Enzyme activation,Type 2 diabetes (T2D),Metabolic stability,Indazolone,N-arylation and cyclization
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