GABAB receptors resist acute desensitization in both postsynaptic and presynaptic compartments of periaqueductal gray neurons.

Neuroscience Letters(2013)

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摘要
•GABABR activation resists desensitization in both pre- and postsynaptic compartments.•Resisting desensitization at postsynaptic is independent of presynaptic alteration.•Resisting desensitization at presynaptic is independent of postsynaptic alteration.
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关键词
aCSF,AMPA,AP-5,CGP52432,CNS,DNQX,EPSCs,GABA,GDP-β-S,GPCRs,IPSCs,K–S test,LC,PAG,POMC,TTX
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