Methods of coagulation.

The investigation of haemostasis is aimed to replicate normal blood coagulation in the laboratory. There are a number of different methods employed including clot-based coagulation tests, chromogenic assays, immunological tests, and aggregation studies. Today automated machines are designed to be able to perform a number of different methodologies. To guarantee the results produced by a laboratory are reliable and accurate, laboratories need to follow international standards and guidelines and use established methodologies. The laboratory needs a quality management plan, to perform internal quality control and participate in an external quality assurance program.