Quantification of guided regeneration of weight-bearing bones.

An accurate histological evaluation system was established to improve and quantify the compatibility of membranes to provide bone; regeneration in a large mid-diaphyseal bone defect, complementing radio: graphic evaluation. New bone formation obtained in critical segmental defects: covered:with tubular ethyl cellulose membranes-was-examined.: Computerized radiography showed gradual new bone formation, which slows after 6 weeks. In a parallel histomorphological assessment, a characteristic process of new bone formation occurs inside-the confined space and surrounding. tissues. Histological findings are summarized according, to the new scoring system, which clarifies, the mechanism and provides complementary quantification of guided bone regeneration.