Mild hypothermia reduces activated caspase-3 up to 1 week after a focal cerebral ischemia induced by endothelin-1 in rats.

Tine Zgavc,Deborah De Geyter,An-Gaëlle Ceulemans,Wendy Stoop,Said Hachimi-Idrissi,Yvette Michotte,Sophie Sarre,Ron Kooijman

Brain Research（2013）

引用 17|浏览6

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摘要

Hypothermia is a promising neuroprotective therapy that has been shown to reduce apoptosis after an ischemic insult. This study evaluated the effect of mild hypothermia on activated caspase-3 up to 1 week after the induction of a stroke.

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关键词

Hypothermia,Cerebral ischemia,Endothelin-1,Cerebral blood flow,Activated caspase-3

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