Somatic mutation of PIK3R1 gene is rare in common human cancers.

Sang Wook Park,Mi Ran Kang,Hyeon Seok Eom,Ji Youn Han,Chang Hyeok Ahn,Sung Soo Kim,Sug Hyung Lee,Nam Jin Yoo

Acta oncologica (Stockholm, Sweden)（2010）

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摘要

The PI3K signaling pathway regulates many normal cellular processes, and perturbation of the PI3K signaling results in deregulated kinase activity and malignant transformation [1]. Phosphatidylinos...

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somatic mutation

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