Common variants in the HLA-DRB1 – HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis

NATURE GENETICS（2013）

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摘要

Jenefer Blackwell, Peter Donnelly and colleagues report a genome-wide association study for visceral leishmaniasis using studies from India and Brazil, with replication in an additional Indian study. They identify common variants at the HLA-DRB1 – HLA-DQA1 HLA class II region associated with susceptibility to visceral leishmaniasis.

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关键词

Genetic predisposition to disease,Genetic variation,Genome-wide association studies,Parasitic infection,Biomedicine,general,Human Genetics,Cancer Research,Agriculture,Gene Function,Animal Genetics and Genomics

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