Synthesis of spirolactone-type diterpenoid derivatives from kaurene-type oridonin with improved antiproliferative effects and their apoptosis-inducing activity in human hepatoma Bel-7402 cells.
European Journal of Medicinal Chemistry（2013）
Key words
Spirolactone-type diterpenoid,Oridonin,Anti-proliferative activity,Apoptosis,Structure–activity relationship
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