Gene Expression Mining in Type 2 Diabetes Research.

TYPE 2 DIABETES: METHODS AND PROTOCOLS, 2ND EDITION(2020)

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摘要
Gene expression analysis by microarray and more recently by next-generation sequencing has become a core part of biomedical research and its value can be seen in thousands of research papers. A successful gene expression experiment needs to be augmented by specialized data mining techniques if the data are to be fully exploited. Here, tools that concentrate on three areas-gene enrichment analysis, literature mining, and transcription factor binding site analysis-are described for the novice user of microarray and next generation sequencing technologies. The focus of this chapter is on free, publicly available, web-based tools.
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关键词
Bioinformatics,Data mining,Gene enrichment,Gene expression,Literature mining,Microarray,Next generation sequencing,Transcription factor binding site
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