Different regulatory and cytotoxic CD4+ T lymphocyte profiles in renal transplants with antibody-mediated chronic rejection or long-term good graft function.

Fulvia Giaretta,Stefania Bussolino,Silvia Beltramo,Fabrizio Fop,Maura Rossetti,Maria Messina,Vincenzo Cantaluppi,Andrea Ranghino,Elisa Basso,Giovanni Camussi,Giuseppe Paolo Segoloni,Luigi Biancone

Transplant Immunology（2013）

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摘要

Comparative analysis of the different subsets of CD4+ T-lymphocytes may provide hints on the immunologic mechanisms operating in the long-term fate of a kidney transplant.

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关键词

Tregs,CTL,mAbs,GzmA,GzmB,Perf,NHS,LTKT,MTKT,AMCR,sCr,FoxP3,CTLA-4,TNF,GITR,IL-7,MHC-II,HLA,MMF,CsA,Tac,mTORi,AZA,CIN,ST,ESRD,APKD,PRA,FITC,PE,TC,FCM,PBS,FACS,APC

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