Improvement of migraine after patent foramen ovale percutaneous closure in patients with subclinical brain lesions: a case-control study.

Carlo Vigna,Nicola Marchese,Vincenzo Inchingolo,Giuseppe Maria Giannatempo,Michele Antonio Pacilli,Pietro Di Viesti,Matteo Impagliatelli,Rosaria Natali,Aldo Russo,Raffaele Fanelli,Francesco Loperfido

JACC. Cardiovascular interventions（2009）

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摘要

In migraineurs with a large PFO and subclinical brain MRI lesions, a significant reduction in frequency and severity of migraine recurrence can be obtained by PFO closure when compared with frequency and severity in controls.

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