Aryl-heteroaryl derivatives as novel wake-promoting agents.

Brigitte Lesur,Yin G Lin,Val R Marcy,Lisa D Aimone,John Gruner,Edward R Bacon,Sankar Chatterjee

CHEMICAL BIOLOGY & DRUG DESIGN（2013）

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摘要

In search of a next generation molecule to the novel wake-promoting agent modafinil, a series of aryl-heteroayl-derived wakefulness enhancing agents (in rats) was developed. From this work, compound 16 was separated into its enantiomers to profile them individually.

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关键词

aryl,heteroaryl,modafinil,transporters,wake-promoting agents

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