Zymosan induces NADPH oxidase activation in human neutrophils by inducing the phosphorylation of p47phox and the activation of Rac2: involvement of protein tyrosine kinases, PI3Kinase, PKC, ERK1/2 and p38MAPkinase.
Biochemical Pharmacology（2013）
摘要
Pathways involved in zymosan-induced NADPH oxidase (NOX2) activation in human neutrophils.
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关键词
Neutrophils,NADPH oxidase,p47phox,Rac2,ROS,Signaling
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