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Development of Macrocyclic Inhibitors of Hcv Ns3/4a Protease with Cyclic Constrained P2-P4 Linkers

Michael T. Rudd,Charles J. McIntyre,Joseph J. Romano,John W. Butcher,M. Katharine Holloway,Kimberly Bush,Kevin T. Nguyen,Kevin F. Gilbert,Terry A. Lyle,Nigel J. Liverton,Bang-Lin Wan,Vincenzo Summa,Steven Harper,Michael Rowley,Joseph P. Vacca,Steven S. Carroll,Christine Burlein,Jillian M. DiMuzio,Adam Gates,Donald J. Graham,Qian Huang,Steven W. Ludmerer,Stephanie McClain,Carolyn McHale,Mark Stahlhut,Christine Fandozzi,Anne Taylor,Nicole Trainor,David B. Olsen,John A. McCauley

Bioorganic & Medicinal Chemistry Letters（2012）

引用 10|浏览31
关键词
Hepatitis C,NS3/4A protease,Macrocycle,P2-P4 linker,Cyclic constraint
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