Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

Carolina E. Hagberg,Annika Mehlem,Annelie Falkevall,Lars Muhl,Barbara C. Fam,Henrik Ortsäter,Pierre Scotney,Daniel Nyqvist, Erik Samén,Li Lu,Sharon Stone-Elander,Joseph Proietto, Sofianos Andrikopoulos,Åke Sjöholm,Andrew Nash,Ulf Eriksson

NATURE（2012）

引用 304|浏览11

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摘要

Inhibition of VEGF-B signalling is shown to limit ectopic fatty-acid accumulation, restore peripheral insulin sensitivity and muscle glucose uptake, and preserve pancreatic islet functionality.

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关键词

Medical research, Cell biology, Physiology, Biochemistry

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