The physical state of lipid substrates provides transacylation specificity for tafazzin

Michael Schlame,Devrim Acehan,Bob Berno,Yang Xu,Salvatore Valvo,Mindong Ren,David L Stokes,Richard M Epand

Nature chemical biology（2012）

引用 95|浏览5

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摘要

Tafazzin, the mitochondrial transacylase that is deficient in Barth syndrome, selects lipid substrates in the inverted hexagonal phase but does not react with bilayer lipids.

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nature chemical biology, science

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