Prevalence of protease and reverse transcriptase drug resistance mutations over time in drug-naïve human immunodeficiency virus type 1-positive individuals in Rio de Janeiro, Brazil.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY(2002)
摘要
The prevalence of mutations that confer resistance to protease inhibitors and to nucleoside and normucleoside reverse transcriptase inhibitors in 49 blood samples from drug-naive human immunodeficiency virus type 1-infected blood donors living in Rio de Janeiro state, Brazil, in 1998 was evaluated genotypically and phenotypically.
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关键词
drug resistance,mutation,phylogeny,phenotype,reverse transcriptase,hiv reverse transcriptase,genotype
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