Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene and arterial oxygen saturation at high altitude

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, pp. 362-366, 2002.

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Keywords:
angiotensin-converting enzymepolymorphismaltitudeoxygen saturation

Abstract:

There is a significant genetic influence on arterial oxygen saturation (SaO(2)) in high-altitude (HA) residents. It is not known whether this is true of lowlanders ascending to HA. The I allele of the angiotensin-converting enzyme (ACE) gene is associated with low ACE activity and elite endurance performance. An excess of the 1 allele has...More

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