Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene and arterial oxygen saturation at high altitude

    American journal of respiratory and critical care medicine, Volume 166, Issue 3, 2002, Pages 362-366.

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    Keywords:
    oxygen saturationaltitudepolymorphismhigh altitudeangiotensin converting enzyme

    Abstract:

    There is a significant genetic influence on arterial oxygen saturation (Sa(O(2))) in high-altitude (HA) residents. It is not known whether this is true of lowlanders ascending to HA. The I allele of the angiotensin-converting enzyme (ACE) gene is associated with low ACE activity and elite endurance performance. An excess of the I allele h...More

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