DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis

Yu-Ting Yang,Chia-Lin Wang,Linda Van Aelst

NATURE NEUROSCIENCE（2012）

引用 77|浏览7

暂无评分

摘要

This study describes how interactions between DOCK7 and TACC3 are key to the switch from proliferation to differentiation in developing radial glial progenitor cells (RGCs). DOCK7 exerts its effects via interactions with the centrosome-associated protein TACC3, and these interactions are likely to modulate the RGCs' apically directed interkinetic nuclear migration.

查看译文

关键词

Cell migration,Developmental neurogenesis,Gene regulation,Molecular neuroscience,Biomedicine,general,Neurosciences,Behavioral Sciences,Biological Techniques,Neurobiology,Animal Genetics and Genomics

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要