Cytotoxic T lymphocytes: Sniping cancer stem cells.

Yoshihiko Hirohashi,Toshihiko Torigoe,Satoko Inoda,Rena Morita,Vitaly Kochin,Noriyuki Sato

Oncoimmunology（2012）

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摘要

Cancer stem cells (CSCs)/cancer-initiating cells (CICs) are characterized as a small population of cancer cells that have high tumor-initiating ability. CSCs/CICs are resistant to several cancer therapies, and eradication of CSCs/CICs is essential to cure cancer. How can we eradicate CSCs/CICs? Cytotoxic T lymphocytes (CTLs) might be a promising answer.

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