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Finger-loop Inhibitors of the HCV NS5b Polymerase. Part 1: Discovery and Optimization of Novel 1,6- and 2,6-Macrocyclic Indole Series.

David McGowan,Sandrine Vendeville,Tse-I Lin,Abdellah Tahri,Lili Hu,Maxwell D. Cummings,Katie Amssoms,Jan Martin Berke,Maxime Canard,Erna Cleiren,Pascale Dehertogh,Stefaan Last,Els Fransen,Elisabeth Van der Helm,Iris Van den Steen,Leen Vijgen,Marie-Claude Rouan,Gregory Fanning,Origene Nyanguile,Kristof Van Emelen,Kenneth Simmen,Pierre Raboisson

Bioorganic & Medicinal Chemistry Letters（2012）

Cited 20|Views29
Key words
Hepatitis C virus,NS5b polymerase,Allosteric inhibitor,Macrocycle
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