Organ-specific fungal infections as a complication of treatment of children with cancer. A single centre observation]

Increasing intensity of treatment of childhood malignancies as well as administration of the new generation broad-spectrum antibiotics is associated with increased risk of fungal infections. In this paper, we describe two patients, in whom anti-neoplastic treatment was complicated by systemic fungal infection. Early suspicion and/or detection of fungal infection enables more effective and shorter treatment. Administration of an anti-fungal drug should be considered in every neutropenic patient after chemotherapy and/or with protracted fever. Since the anti-fungal treatment is usually prolonged, this results in significant interruption of the chemotherapy.