Diversity oriented one-pot three-component sequential synthesis of annulated benzothiazoloquinazolines

Organic and medicinal chemistry letters(2012)

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摘要
Annulated benzothiazoloquinazolines have been synthesized by a diversity oriented simple and convenient synthesis involving one-pot three-component reaction of substituted 2-aminobenzothiazoles with α-tetralone and aromatic/heteroaromatic aldehydes in ethanol in the presence of catalytic amount of triethylamine. The synthesized compounds have been characterized by their elemental analyses and spectral data.
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medicinal chemistry,organic chemistry,biomedical research,bioinformatics
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