A split ligand for lanthanide binding: facile evaluation of dimerizing proteins.
CHEMICAL COMMUNICATIONS(2012)
摘要
Luminescence of lanthanides is attractive for biological applications due to its long lifetime and sharp emission profiles. We describe the split display of a lanthanide binding ligand that allows facile evaluation of dimerizing proteins. The split lanthanide ligand is cysteine reactive, and therefore should be readily applicable to a variety of protein systems.
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