Neutrophil function in small animals.

Neutrophils are motile phagocytes traditionally recognized for their role in innate immunity, representing the initial effector cell to eliminate bacterial and fungal pathogens. New evidence has highlighted their importance in numerous other processes, including the promotion and resolution of inflammation, amplification of adaptive immunity, and coagulation. Neutrophils are able to phagocytose and kill microbes, and create extracellular traps to ensnare and eradicate extracellular pathogens. Many of their diverse functions are linked to preformed proteins and effector molecules stored in granules. The importance of neutrophil function for animal health is emphasized through the discussion of inherited disorders of neutrophil function.