High tidal volume mechanical ventilation-induced lung injury in rats is greater after acid instillation than after sepsis-induced acute lung injury, but does not increase systemic inflammation: an experimental study

    BMC anesthesiology, Volume 11, Issue 26, 2011, Pages 26-26.

    Cited by: 22|Bibtex|Views0|Links
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    Keywords:
    Ventilator-induced lung injuryacute lung injurysepsiscytokineslung histologyMore(1+)

    Abstract:

    To examine whether acute lung injury from direct and indirect origins differ in susceptibility to ventilator-induced lung injury (VILI) and resultant systemic inflammatory responses.Rats were challenged by acid instillation or 24 h of sepsis induced by cecal ligation and puncture, followed by mechanical ventilation (MV) with either a low ...More

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