The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis

Merit Cudkowicz,Michael E Bozik,Evan W Ingersoll,Robert Miller,Hiroshi Mitsumoto,Jeremy Shefner,Dan H Moore,David Schoenfeld,James L Mather,Donald Archibald,Mary Sullivan, Craig Amburgey,Juliet Moritz,Valentin K Gribkoff

NATURE MEDICINE（2011）

引用 177|浏览15

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摘要

myotrophic lateral sclerosis (ALS) is a neurodegenerative disease that primarily affects motor neurons. Now, Valentin Gribkoff and his colleagues show some preliminary evidence that the drug dexpramipexole may have clinical activity in a small placebo-controlled trial in patients with ALS.

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nature medicine, science

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