Evaluation of the audiological characteristics of 3251 cases who failed the newborn hearing screening in Guangzhou]

To analyze the audiological characteristics of the cases who failed the newborn hearing screening under the two hearing screening programs (OAE and AABR) in two different screening population(with or without high-risk of hearing loss).Three thousand two hundred and fifty-one babies (6502 ears) who failed the hearing screening twice or more and then failed in the audiological evaluation are included in the research. The cases were divided into two groups by the time accepting the screening, < 6 (2683 cases) months or > or = 6 months (568 cases), and then analyze the effect of age on the audiological characteristics. Compare the sensitivity and specificity of different hearing screening programs, OAE or AABR. Evaluate the audiological characteristics between the groups with or without the high-risk factors of hearing loss. Total of them were performed detailed audiological evaluation including in ABR, DPOAE, acoustic immittance, and some of them accepted ASSR test and computer tomography.85.30% to 86.54% infants accepted initial screening in Guangzhou city, and less than 64. 10% infants underwent rescreening. 0.0282% or 0.0220% infants needed immediately early intervention. The group without high-risk factors was less likely to suffer from mild to profound hearing loss than those with high-risk factors. According to different hearing screening programs, more cases passed the OAE hearing screening and more cases were diagnosed profound hearing loss under AABR screening.AABR screening technology is better than OAE screening. The target population is the infants with risk factors, so perinatal history record is very important. The percentage of population who need immediately early intervention is more than 0.0282%-0.0220%.