Lipid nanoparticle purification by spin centrifugation-dialysis (SCD): a facile and high-throughput approach for small scale preparation of siRNA-lipid complexes.
International Journal of Pharmaceutics（2011）
摘要
Knock down in luciferase mice over 15 days using lipid nanoparticles encapsulating an anti-luciferase sequence.
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关键词
siRNA,Lipid Nanoparticle (LNP),Spin Centrifugation–Dialysis (SCD),Encapsulation,Tangential Flow Filtration (TFF),Liposome
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