The peroxiredoxin repair proteins.
Sub-cellular biochemistry(2007)
摘要
Sulfiredoxin and sestrin are cysteine sulfinic acid reductases that selectively reduce or repair the hyperoxidized forms of
typical 2-Cys peroxiredoxins within eukaryotes. As such these enzymes play key roles in the modulation of peroxide-mediated
cell signaling and cellular defense mechanisms. The unique structure of sulfiredoxin facilitates access to the peroxiredoxin
active site and novel sulfur chemistry
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关键词
sestrin,cysteine sulfinic acid,retroreduction,sulfiredoxin,signal transduction,oxidation reduction,heat shock proteins
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