A novel series of parenteral cephalosporins exhibiting potent activities against Pseudomonas aeruginosa and other Gram-negative pathogens: synthesis and structure-activity relationships.

Bioorganic & Medicinal Chemistry(2007)

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摘要
A novel series of cephalosporins bearing a chlorominothiazole and a carboxymethoxyimino moiety at the C-7 side chain was prepared, and their antibacterial activities were evaluated.
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关键词
Cephalosporin,β-Lactamase,Resistant,Gram-negative bacterium,Pseudomonas aeruginosa,Extended spectrum β-lactamase
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