The influence of HIV infection and antiretroviral therapy on the mitochondrial membrane potential of peripheral mononuclear cells.

Thomas Sternfeld, Mathias Schmid,Annette Tischleder, Susanne Mudra, Angelika Schlamp, Bernd P Kost, Rudolf Gruber,Mike Youle,Johannes R Bogner, Frank-Detlef Goebel

Antiviral therapy（2007）

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摘要

In HIV-infected persons delta psi m is significantly reduced. Patients with lipoatrophy have significantly reduced delta psi m. This is the first study showing that the delta psi m of PBMCs is highly correlated with CD4+ T-cell count in HIV infection.

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关键词

Antiretroviral Therapy,HIV,HIV Infection

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