Weight-based loading of vancomycin in patients on hemodialysis.

Merideth Brown,Radhika Polisetty,Edward J Gracely,Bulent Cuhaci,Hans P Schlecht

CLINICAL INFECTIOUS DISEASES（2011）

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摘要

We evaluated weight-based loading doses of vancomycin and resulting initial prehemodialysis concentrations. Modeling demonstrated modest correlation between dose administered, age, and initial concentration achieved. Actual body weight-based loading of vancomycin predictably achieves therapeutic initial concentrations in patients who receive hemodialysis.

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