A semi-invariant V α 10 + T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen–recognition properties

Type I natural killer T cells are characterized by an invariant V α 14-J α 18 T cell antigen receptor α-chain. Godfrey and colleagues describe a population of CD1d-restricted natural killer T cells that express a previously unidentified canonical V α 10-J α 50 α-chain.