Value Of Beta(2)-Microglobulin In The Serum Of Healthy Subjects Older Than 40 Years

The aim of this research was to determine if the age of healthy subjects older than 40 years of age has an influence on the concentration of beta(2)-microglobulin in the serum of subjects of different populations. We examined the values of beta(2)-microglobulin in the serum of 51 healthy subjects aged 40-86 years using the microparticle enzyme immunoassay AxSYM beta(2)-microglobulin test. The reference values of beta(2)-microglobulin according to the nonparametric statistical method is 0.95-2.73 mg/L. A correlation was found between beta(2)-microglobulin and age: 40-50 years (0.94-1.54 mg/L), 51-65 years (0.96-2.62 mg/L), and > 65 years (1.13-2.84 mg/L). There was no significant statistical difference of beta(2)-microglobulin between genders (P > 0.05); however, there was a statistically significant difference between the concentration of beta(2)-microglobulin and the subjects' age. (Spearman's rank correlation coefficient rho = 0.66; P < 0.01). A direct correlation between age and the concentration of beta(2)-microglobulin was observed. This research is a contribution to determining reference values of beta(2)-microglobulin in subjects of different populations.