Transoral robotic surgery for oropharyngeal carcinoma and its impact on patient-reported quality of life and function.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK(2012)

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摘要
Background The aim of this study was to assess the quality of life of patients with oropharyngeal squamous cell carcinoma after transoral robotic surgery (TORS). Methods. Short Form (SF)-8 and Performance Status Scale (PSS) questionnaires were completed prior to surgery, 6 and 12 months of follow-up. Results. In all, 38 patients treated with TORS followed by adjuvant therapy as indicated were prospectively enrolled. For PSS Eating and Diet domains, significant decreases occurred at 6 months (p <= .001 and p <= .001, respectively) but not at 12 months. Significant declines in PSS Speech were seen at 6 and 12 months (p <= .001 and p <= .001). There were no significant declines in the SF-8 domains, except for Bodily Pain and Global Health (6 months). Significantly higher PSS Eating and Diet scores were seen at 6 months for TORS alone compared with TORS and chemoradiation. Conclusions. Combination TORS and adjuvant therapy caused a temporary decrease in several domains at 6 months, returning to baseline including swallowing function in all patients. (C) 2011 Wiley Periodicals, Inc. Head Neck 34: 146-154, 2012
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关键词
transoral robotic surgery (TORS),postoperative radiotherapy,postoperative chemoradiation,oropharynx carcinoma,quality of life,functional status
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